Pregnancy: Adverse events have not been observed in animal reproduction studies. Spontaneous abortion has been observed in pregnant women during clinical trials, although a causal association with prucalopride has not been established. Use during pregnancy is not recommended. Women of childbearing potential should employ effective contraception during therapy.
Lactation: Prucalopride is excreted in breast milk. In the absence of human data in women who actively breast-feeding, breast-feeding is not recommended.